Indication
To aid in the development of immunity against coccidiosis in chickens.
Presentation
1000 doses of live coccidian oocysts per vial (Eimeria acervulina, E. brunetti, E. maxima, E. necatrix and E. tenella).
Vaccination Program
One dose of live coccidian oocysts given during or after placement.
Vaccine administration
From 1 day-of-age to 5 days-of-age administer Immucox® II by gel spray, in drinking water or edible gel puck.

Immucox-II Vaccination Program
Precautions
Store refrigerated at 3 to 7ºC. Do not allow to freeze.
See Immucox® II package insert for detailed Directions for Use.
Immucox® II registered pursuant to the ACVM Act 1997, No. A9383. See www.foodsafety.govt.nz for registration conditions.
Further Information
Management of Immucox® Breeders and Layers recycling and sporulation.
Chickens develop immunity against coccidiosis without getting disease if exposed to 3 cycles of infection with a small number of coccidians.
Immucox® II vaccine provides the correct dose of oocysts for the first cycle of infection. The vaccine is given by 1 of 3 methods:
1. in drinking water thickened with gel, 2. in a gel spray, or 3. in a gel puck.
The oocysts hatch in the birds’ gut and the coccidians multiply.
After about 5 days the next generation of oocysts are shed in faeces and onto the litter.
The second and third cycles of infection occur when the chicks eat the oocysts in the litter. Each cycle takes 6 to 10 days.
The oocysts on the litter must sporulate to become infective.
Sporulation requires warm temperature (25 to 30ºC), moisture and oxygen.
Temperature, bird density, and litter moisture must be managed to ensure sporulation and successful completion of the second and third cycles of infection.
Low bird density may result in dry litter, inadequate sporulation and inadequate intake of oocysts. High bird density may result in excessive intake of oocysts.
If chick density on placement is greater than 30 birds / m2, the surrounds must be opened no later than the 5th day after vaccination to allow 30 birds / m2.
Management of oocyst sporulation in the litter between 6 and 10 days after vaccination is critical. Do not allocate extra space or transfer birds during the period 6 to 10 days after vaccination. If the litter becomes dry and dusty, water needs to be sprinkled on the litter with a watering can, knapsack sprayer or hose.
On day 11 expand the area to allocate 15 birds / m2.
On day 17 birds can be allowed unrestricted space.
Chicks should not be transferred to pens with new litter before 28 days-of-age.
Anticoccidial drugs must not be used. They interfere with the recycling of oocysts.
Broad spectrum antibiotics or antibacterials with anticoccidial activity, such as tetracyclines, sulphonamides or nitrofurans, should not be given until 12 days have elapsed after vaccination.
During the second cycle (6 -10 days) and third cycle (12 – 17 days) some birds may show signs of coccidiosis such as lack of movement, ruffled feathers, lack of appetite, diarrhoea and bloody faeces. This shows the vaccine is cycling. The signs of disease should disappear in two days without increased mortality.
Restricted Veterinary Medicine (RVM), veterinary authorisation required for purchase and use.
Disease Information Sheet
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Safety Data Sheet